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KMID : 1084220210280040242
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Journal of Rheumatic Diseases
2021 Volume.28 No. 4 p.242 ~ p.246
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A Case of Overlap Syndrome of Systemic Sclerosis and Cryoglobulinemic Vasculitis With Central Nervous System Involvement
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Jung You-Jin
Lee Eun-Young Emily
Yeo Ji-Na
Kim Mi-Hyeon
Choi Se-Rim
Song Yeong-Wook
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Abstract
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Mixed cryoglobulinemic vasculitis (CV) is occasionally caused by autoimmune diseases including systemic sclerosis. Multiorgan involvement such as skin, kidney, and peripheral nerve involvement is common in mixed CV. However, central nervous system (CNS) involvement is extremely rare. Here, we report a case of overlap syndrome of limited cutaneous systemic sclerosis and mixed cryoglobulinemic vasculitis with CNS involvement. The neurologic deficits and systemic symptoms improved promptly after steroid and cyclophosphamide therapy.
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KEYWORD
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Cryoglobulinemia, Vasculitis, Central nervous system, Scleroderma, systemic
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